PFO Post Closure ” Do I take these pills for life? “


Once a hole in the heart is plugged with a PFO closure device the common question asked by patients is how long does one need to continue antiplatelet therapy?   According to a new analysis reported in The Journal of the American College of Cardiology, long-term follow-up of patients who underwent patent foramen ovale (PFO) […]

Another PFO trial shows evidence of better outcomes for stroke patients following PFO closure


The findings support results of several trials and suggest that patients with a higher-risk #PFO are likely to benefit from a pfo closure device. According to findings presented at the 67th American College of Cardiology’s Annual Scientific Session,  patients who received a medical device to close a patent foramen ovale (PFO) after a stroke fared better […]

Are patients with a patent foramen ovale at increased risk of perioperative ischemic stroke?


Posted by David Dansereau for Know-Stroke.org As reported in the February 6, 2018 issue of the Journal of the American Medical Association  | Source:  JAMA. 2018;319(5):452-462.   This study tested the hypothesis that a preoperatively diagnosed PFO is associated with increased risk of perioperative ischemic stroke among patients undergoing noncardiac surgery. Summary of Findings: For adults undergoing non-cardiac surgery, […]

Are cardiologists and neurologists finally working together to find consensus on the role of patent foramen ovale (PFO) closure after stroke?


The decision to close a PFO after a stroke should certainly only be made after extensive testing and collaboration by patients and clinicians working closely together.  From my experience being involved as a stroke patient advocate and following the stories of cryptogenic stroke patients with PFO over time, I’ve learned first hand that part of […]

GORE® CARDIOFORM Septal Occluder used in REDUCE trial returns positive results


According to recent Gore announcement, their PFO closure device  showed a statistically significant reduction in stroke recurrence in the primary intent-to-treat analysis.  Read the full Gore press release here…  

FDA approves Amplatzer


News announcement from FDA you’ll be interested in if you’ve suffered a cryptogenic stroke from a suspected PFO and need more choice for treatment

FDA Circulatory System Devices Panel Votes to Approve Amplatzer PFO Occluder


Post by David Dansereau,MSPT Know-Stroke.org On May 24,2016 I provided patient testimony at the Circulatory System Device Panel at the FDA along with Bray Patrick-Lake and Peggy Mahrt of the PFO Research Foundation and several other patients who also traveled to Washington DC to share their stories.   I wanted to share my FDA  testimony […]

Is PFO closure now a black hole for medicine?


-by David Dansereau,MSPT  Know-Stroke.org I admit, I was drifting in thought as I watched the movie Interstellar with my boys over the weekend. The 2014 movie stars Matthew McConaughey who plays Cooper, an ex-pilot who must leave his family on Earth behind to lead an expedition beyond our galaxy through a black hole to discover […]

FDA Announces First-Ever Patient Engagement Advisory Committee


FDA Announcement on New Patient Engagement Initiative Source FDA Today the FDA is announcing the establishment of the Patient Engagement Advisory Committee (PEAC) to help assure that the needs and experiences of patients are included as part of the FDA’s deliberations on complex issues relating to the regulation of medical devices and their use by patients. While […]

New Report Released : Closure versus medical therapy for preventing recurrent stroke in patients with patent foramen ovale and a history of cryptogenic stroke or transient ischemic attack


PFO Closure vs. Medical Therapy Published Sept. 8 2015 Cochrane.org The authors of this report wanted to compare the safety and effectiveness of transcatheter device closure (TDC) versus medical therapy in people with a patent foramen ovale (PFO) who have suffered a stroke of unknown cause in order to prevent strokes or similar events occurring again. Key results: The Cochrane […]